Specification of neurotransmitter phenotypes in Xenopus laevis

The role of voltage-gated calcium channels in neurotransmitter phenotype specification: Coexpression and functional analysis in Xenopus laevis

Calcium activity has been implicated in many neurodevelopmental events, including the specification of neurotransmitter phenotypes. Higher levels of calcium activity lead to an increased number of inhibitory neural phenotypes, whereas lower levels of calcium activity lead to excitatory neural phenotypes. Voltage-gated calcium channels (VGCCs) allow for rapid calcium entry and are expressed duri...

ترتیب اعصای جانبی در دم لارو of Xenopus laevis

Inhibitors of metalloendoprotease activity prevent K+-stimulated neurotransmitter release from the retina of Xenopus laevis.

Metalloendoprotease activity was identified in retinal homogenates using a synthetic fluorogenic metalloendoprotease substrate and specific metalloendoprotease inhibitors. The requirement of metalloendoprotease activity in neurotransmitter release was examined during the depolarization-induced release of [3H]glycine from the retina of Xenopus laevis. Neurons with high affinity uptake and calciu...

Cortical grafting in Xenopus laevis.

T H E amphibian egg bears a cortex as the periphery of its cytoplasm. The interpretation by Dalcq & Pasteels (1937) of experiments performed by Pasteels (1938, 1940, 1941), in which fertile eggs of Rana fusca were centrifuged or inverted, led to the suggestion that the cortex possesses properties which control the course of development to some degree. It appeared that the properties of the cort...

Antiporter in Xenopus Laevis Oocytes

The amiloride-sensitive Na + /H + antiporter in defolliculated oocytes of Xenopus laevis was characterized by measurements of H Na + influx and apparent H + efflux. Uptake of ^Na"" was linear over a 90-min incubation period and was inhibited approximately 80% with 5xlO~moll~ amiloride. Amiloride-sensitive sodium uptake was reduced following collagenase treatment or oocyte aging. Ko 5 for amilor...